Increased nephrogenous endothelin generation during radiocontrast administration
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چکیده
منابع مشابه
Radiocontrast agents induce endothelin release in vivo and in vitro.
The intravascular administration of the ionic radiocontrast agent sodium iothalamate (2.9 g of iodine/kg body wt) to rats induced an increase in plasma concentration of immunoreactive endothelin from 21.3 +/- 1.2 to 36 +/- 3 fmol/mL, preceded by a transient rise in the plasma level of atrial natriuretic peptide and associated with a fall in RBF. Equi-iodine amounts of the nonionic agents ioxagl...
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BACKGROUND/AIMS Parstatin is a 41-mer peptide formed by proteolytic cleavage on activation of the protease-activated receptor 1. Parstatin was recently found to be cardioprotective against myocardial ischemia/reperfusion (IR) injury. In the present study, it was hypothesized that parstatin would protect the kidneys in acute renal failure. METHODS We investigated the effects of parstatin on th...
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the head for evaluation of memory loss. She received 100 ml of diatrizoate meglumine (Angiovist 282), an intravenous RCM. The patient had never previously been exposed to RCM and within 1 mm of its administration, she complained of severe dyspnea and a sensation of fullness in her neck, as if someone were choking her. The radiologist evaluating the patient did not report evidence of facial swel...
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An abstract ofthis work appeared in 1976. Clin. Res. 24: 456A. (Abstr.) Dr. Broadus' present address is Division of Endocrinology, Department of Internal Medicine, Yale University, New Haven, Conn. 06510. Received for publication 20 April 1976 and in revisedform 13 June 1977. the validity of the measurements and the expressions employed.
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In the past few years cortisone and A.C.T.H. have been used in the treatment of nephritis. In the nephrotic state these drugs frequently produce a diuresis (Farnsworth, 1950a; Luetscher, Deming and Johnson, 1951). In haemorrhagic nephritis, however, the results have been variable (Thorn, Merrill, Smith, Roche and Frawley, 1950; Heller, Jacobson and Hammarsten, 1951). The present paper reports a...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1991
ISSN: 0735-1097
DOI: 10.1016/0735-1097(91)91518-j